The CIRS Group Podcast

Candid conversations about healing, community, and CIRS recovery — hosted by Barbara and Jacie.

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Featured Episodes

Dr. Andrew Heyman on the Cell Danger Response: Why CIRS Patients Stall & How to Heal Beyond Mold

On this episode of The CIRS Group podcast, hosts Jacie and Barbara interview Dr. Andrew Heyman about Dr. Naviaux’s cell danger response (CDR) framework and why it can explain stalled ...recoveries in chronic mold-related illness and CIRS. Heyman describes how mitochondrial “danger mode” drives three phases: initial inflammation (innate immune activation), rebuilding via aerobic glycolysis, and reintegration requiring “all clear” signals like VIP, which positions CIRS as a subset of CDR. He emphasizes total toxic load (mold/biotoxins plus chemicals, metals, infections, gut-derived endotoxins, physical trauma, and emotional trauma), and discusses the neuroendocrine-immune axis (VIP, MSH, PACAP) and autonomic/vagal tone as key to recovery. He outlines his BeyondMold.com five-phase clinical program: environment/binders and chemical detox support, pathogen work, gut optimization, metabolic/hormone rebuilding with nervous system support, and a final readiness-to-heal/phenotyping phase using targeted safety signals (including VIP forms).

TIMESTAMPS
00:00 Intro to Dr. Andrew Heyman
02:38 What Is Cell Danger Response?
06:38 CIRS in the context of Cell Danger Response: changing gene expression
12:18 The role of total toxic load and co-infections
16:52 How the nervous system is affected by Cell Danger Response
22:27 Why having a solid practitioner in your corner is so important
23:56 The limitations of CIRS diagnostic testing
28:47 Beyond Mold framework for healing in five phases
37:18 Are you ready to heal?
46:16 Advice for stalled patients
51:14 How to work with Dr. Heyman and Beyond Mold

For more information and support, join us at https://thecirsgroup.com

WORK WITH DR. HEYMAN: https://beyondmold.com/
Dr. Heyman Q&A mentioned in the outro: https://www.youtube.com/live/EWoki09eHhk

Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs

The CIRS Group:
Support Community: https://thecirsgroup.com
Instagram: https://www.instagram.com/thecirsgroup/

Find Jacie for carnivore, lifestyle and limbic resources:
Jacie’s book on the Carnivore diet! https://a.co/d/8ZKCqz0
Instagram: https://www.instagram.com/ladycarnivory
YouTube: https://www.youtube.com/@LadyCarnivory
Blog: https://www.ladycarnivory.com/

Find Barbara for business/finance tips and coaching:
Website: https://www.actlikebarbara.com/
Instagram: https://www.instagram.com/actlikebarbara/
YouTube: https://www.youtube.com/@actlikebarbara

Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.Show More

Dr. Andrew Heyman on the Cell Danger Response: Why CIRS Patients Stall & How to Heal Beyond Mold

On this episode of The CIRS Group podcast, hosts Jacie and Barbara ...

Are you making this mistake?

Finding mold can create a sense of urgency. Many people immediately ...

How to get a better brain 🧠

Is your brain too big or too small? To find out how to get the ...

GB feeling NORMAL 🙏

God bless feeling normal! To check out the LAST (and best) phase of ...

Wake up, babe, phase five just dropped 🎤

We completed all of the Shoemaker phases! Go us! To see all FIVE ...

Phase 5: Restore brain volume and repair inflammation markers (Shoemaker Protocol Series)

Barbara and Jacie wrap up their five-part Shoemaker Protocol series ...

Barbara and Jacie wrap up their five-part Shoemaker Protocol series with Phase 5: Repair and Restore. This phase focuses on normalizing innate immune markers (MMP-9, C3a, C4a, and TGFb1) and ...restoring brain volume. They explain that low-starch/gluten-free diet helps bring down MMP-9, while persistently elevated C3a/C4a or TGFb1 often signal ongoing exposure, gut issues, tick-borne illness, or dental cavitations. The episode culminates with VIP (vasoactive intestinal peptide) nasal spray (the most anticipated step of the entire protocol!) which supports anti-inflammatory pathways, neurological function, and brain volume restoration over 6–12 months.

For more information and support, join us at https://thecirsgroup.com

TIMESTAMPS
00:00 Introduction: Phase Five
01:24 Medical Disclaimer
01:55 Innate Immune Markers and VIP Nasal Spray
02:50 Understanding MMP-9
05:14 C3a and C4a Markers
07:20 TGFb1
08:18 VIP Spray Treatment
10:34 Closing Thoughts

For more information and support, join us at https://thecirsgroup.com

Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs

The CIRS Group:
Support Community: https://thecirsgroup.com
Instagram: https://www.instagram.com/thecirsgroup/

Find Jacie for carnivore, lifestyle and limbic resources:
Jacie’s book on the Carnivore diet! https://a.co/d/8ZKCqz0
Instagram: https://www.instagram.com/ladycarnivory
YouTube: https://www.youtube.com/@LadyCarnivory
Blog: https://www.ladycarnivory.com/

Find Barbara for business/finance tips and coaching:
Website: https://www.actlikebarbara.com/
Instagram: https://www.instagram.com/actlikebarbara/
YouTube: https://www.youtube.com/@actlikebarbara

Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.Show More

YES MOLD IS A BIG DEAL!!! 🫠

YES MOLD IS A BIG DEAL!!! Seriously, send this to the mold-deniers, ...

How often do you pee? ✨

How often do you pee? It might be less normal than you think 🤔 Check ...

Are your hormones outta whack?

Hormone balance is SO important for quality of life! Make sure yours ...

The problem with "detoxing"

The problem with "detoxing" advice in the wellness space is that it ...

Keys to feeling better: Repair metabolism, detox pathways, hormones & electrolytes

In this CIRS Group Podcast episode, Jacie and Barbara cover phase four ...

In this CIRS Group Podcast episode, Jacie and Barbara cover phase four of the Shoemaker Protocol, focused on restoring normal metabolic function after biotoxin elimination. They explain that this phase ...may include supporting detox pathways for “normal” toxins and heavy metals (e.g., daily bowel movements, B vitamins, methylation support, sauna or hot baths, lymphatic techniques, and using binders like charcoal or clay for inorganic toxins), addressing androgen/sex hormone imbalance linked to low MSH (including signs of low testosterone or estrogen dominance, supplementing DHEA), and correcting fluid/electrolyte balance via ADH regulation (symptoms like thirst, frequent urination, nocturia, and static shocks). They discuss electrolyte options, a DIY recipe, and provider-monitored desmopressin if needed, and note this phase can also involve investigating other lingering issues or co-infections before moving to phase five. For more information and support, join us at https://thecirsgroup.com

TIMESTAMPS
00:00 Welcome to Phase Four
01:00 The purpose of repairing damage done by CIRS
03:14 Detox Pathways basics
05:33 Binders for heavy metals
07:05 Androgen & hormone balance
09:40 Fluid and Electrolyte Issues: ADH/Osmolality
12:21 Electrolyte options
14:12 Desmopressin reset explained
15:41 Tidying up and co-infections
17:22 Next Phase and wrap up

For more information and support, join us at https://thecirsgroup.com

LINKS MENTIONED IN THE EPISODE:
Electrolyte caps Barbara uses: https://redmond.life/products/re-lyte-hydration-support-plus-caps
LMNT Recipe (check FAQ): https://drinklmnt.com/pages/ingredients

Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs

The CIRS Group:
Support Community: https://thecirsgroup.com
Instagram: https://www.instagram.com/thecirsgroup/

Find Jacie for carnivore, lifestyle and limbic resources:
Jacie’s book on the Carnivore diet! https://a.co/d/8ZKCqz0
Instagram: https://www.instagram.com/ladycarnivory
YouTube: https://www.youtube.com/@LadyCarnivory
Blog: https://www.ladycarnivory.com/

Find Barbara for business/finance tips and coaching:
Website: https://www.actlikebarbara.com/
Instagram: https://www.instagram.com/actlikebarbara/
YouTube: https://www.youtube.com/@actlikebarbara

Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.Show More

Like healthy people don't worry about it, you know what I mean?

If you are wondering if you have CIRS, you are probably unwell enough ...

March 9, 2025

Repair Your Brain with Plasmalogens – Dr. Dayan Goodenowe

Today we have a special guest! Dr. Dayan Goodenowe is a researcher that has unlocked the power of plasmalogens and thankfully, this is something that can be a real game changer for people struggling with CIRS, or Chronic Inflammatory Response Syndrome.

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